Pat Dryburgh points out that using a web optimized font through Typekit will render ugly in IE if you also use the -webkit-font-smoothing: antialiased trigger in your CSS file. I was using that with this site and turning it off proved to render FF Meta Web Pro a lot better in IE 8 — so to the 3% of you that view this site in IE, you are welcome.
Also if you miss the ‘old’ look install this Safari extension.